why haven't u look at the F.A.Q?
What is PHP-GTK? PHP-GTK is a PHP extension that implements language bindings for GTK+. It provides an object-oriented interface to GTK+ classes and functions and greatly simplifies writing client side cross-platform GUI applications. Why is it not working with the browser/web server? PHP-GTK is not meant to be used in the Web environment. It is intended for creation of standalone applications (run via command-line, user's desktop, etc.).