אתה משתמש בדפדפן מיושן. יתכן והאתר הנוכחי יוצג באופן שגוי, כמו כן אתרים אחרים ברשת.
אנא שדרג את הדפדפן או השתמש בדפדפן חילופי.
אנא שדרג את הדפדפן או השתמש בדפדפן חילופי.
C.M.V - ציטומגלווירוס
- פותח הנושא אמאשלבת3
- פורסם בתאריך
מידע בנושא
והנה קצת תקצירים בנושא: התיעוד על הקשר קייםכבר משנות ה-80 J Autism Dev Disord. 2003 Aug;33(4):455-9. Possible association between congenital cytomegalovirus infection and autistic disorder. Yamashita Y, Fujimoto C, Nakajima E, Isagai T, Matsuishi T. Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, 830-0011 Japan. [email protected] We encountered seven children with symptomatic congenital cytomegalovirus (CMV) infection from 1988 to 1995, of whom two (28.6%) developed typical autistic disorder. Case 1: A boy born at 38 weeks' gestation with a birth weight of 3164 g showed generalized petechiae, hepatosplenomegaly, and positive serum CMV-specific IgM antibodies. He was profoundly deaf, mentally retarded, and exhibited a lack of eye contact, stereotyped repetitive play, and hyperactivity. Case 2: A boy delivered at 39 weeks gestation with a birthweight of 2912 g showed non-progressive dilatation of the lateral ventricles observed postnatally. CMV-specific IgM antibodies were positive and CMV-DNA in the urine was confirmed by PCR. The boy was mentally retarded but not deaf. He showed no interest in people and delayed speech development. Subependymal cysts were detected by cranial ultrasound after birth in both patients. This is the first report describing subependymal cysts and the later development of AD. Cranial magnetic resonance imaging revealed an abnormal intensity area in the periventricular white matter suggestive of disturbed myelination; however, no migration disorders were found in our patients. These findings suggest that the timing of injury to the developing brain by CMV may be in the third trimester in some patients with autistic disorder. ועוד תקציר:Autism as one of several disabilities in two children with congenital cytomegalovirus infection. Ivarsson SA, Bjerre I, Vegfors P, Ahlfors K. Department of Pediatric, University of Lund, Malmo General Hospital, Sweden. Two children with congenital cytomegalovirus (CMV)-infection, severely disabled where autism was one of the disabilities are described. The characterization of the maternal infection have been possible and the connection between congenital CMV-infection and autism is discussed. Autism in a child with congenital cytomegalovirus infection. Markowitz PI. A case is reported of early infantile autism associated with a congenital cytomegalovirus infection. The diagnosis of autism is based on the child's failure to develop good interpersonal relationships, poor eye contact, delayed and deviant use of language, and her rote and nonthematic use of objects and playthings. Resistance to change and self-stimulatory behavior were also present. Onset was before 2 years of age. Congenital cytomegalovirus infection was suggested by the presence of an antibody response to the virus, culture of the virus from the urine, sensorineural hearing loss, and inflammatory damage to the retina of the eye. Although over time improvement was noted, at last examination at the age of 5 years her behavior is still markedly deviant. This and other reported cases suggest that congenital viral infection may be an important cause of infantile autism. It is hypothesized that an ability of the agent to establish chronic infection may predispose to behavioral aberration.
והנה קצת תקצירים בנושא: התיעוד על הקשר קייםכבר משנות ה-80 J Autism Dev Disord. 2003 Aug;33(4):455-9. Possible association between congenital cytomegalovirus infection and autistic disorder. Yamashita Y, Fujimoto C, Nakajima E, Isagai T, Matsuishi T. Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, 830-0011 Japan. [email protected] We encountered seven children with symptomatic congenital cytomegalovirus (CMV) infection from 1988 to 1995, of whom two (28.6%) developed typical autistic disorder. Case 1: A boy born at 38 weeks' gestation with a birth weight of 3164 g showed generalized petechiae, hepatosplenomegaly, and positive serum CMV-specific IgM antibodies. He was profoundly deaf, mentally retarded, and exhibited a lack of eye contact, stereotyped repetitive play, and hyperactivity. Case 2: A boy delivered at 39 weeks gestation with a birthweight of 2912 g showed non-progressive dilatation of the lateral ventricles observed postnatally. CMV-specific IgM antibodies were positive and CMV-DNA in the urine was confirmed by PCR. The boy was mentally retarded but not deaf. He showed no interest in people and delayed speech development. Subependymal cysts were detected by cranial ultrasound after birth in both patients. This is the first report describing subependymal cysts and the later development of AD. Cranial magnetic resonance imaging revealed an abnormal intensity area in the periventricular white matter suggestive of disturbed myelination; however, no migration disorders were found in our patients. These findings suggest that the timing of injury to the developing brain by CMV may be in the third trimester in some patients with autistic disorder. ועוד תקציר:Autism as one of several disabilities in two children with congenital cytomegalovirus infection. Ivarsson SA, Bjerre I, Vegfors P, Ahlfors K. Department of Pediatric, University of Lund, Malmo General Hospital, Sweden. Two children with congenital cytomegalovirus (CMV)-infection, severely disabled where autism was one of the disabilities are described. The characterization of the maternal infection have been possible and the connection between congenital CMV-infection and autism is discussed. Autism in a child with congenital cytomegalovirus infection. Markowitz PI. A case is reported of early infantile autism associated with a congenital cytomegalovirus infection. The diagnosis of autism is based on the child's failure to develop good interpersonal relationships, poor eye contact, delayed and deviant use of language, and her rote and nonthematic use of objects and playthings. Resistance to change and self-stimulatory behavior were also present. Onset was before 2 years of age. Congenital cytomegalovirus infection was suggested by the presence of an antibody response to the virus, culture of the virus from the urine, sensorineural hearing loss, and inflammatory damage to the retina of the eye. Although over time improvement was noted, at last examination at the age of 5 years her behavior is still markedly deviant. This and other reported cases suggest that congenital viral infection may be an important cause of infantile autism. It is hypothesized that an ability of the agent to establish chronic infection may predispose to behavioral aberration.
Copyright©1996-2021,Tapuz Media Ltd. Forum software by XenForo® © 2010-2020 XenForo Ltd.